Navy Captain Wes Masters, newly posted to head the White House Medical Unit, is a physician with only one priority patient, but her job is twenty-four/seven. Her charge is simple—ensure the health and well-being of the most powerful man in the world—the president of the United States. As the First Physician, Wes travels by President Andrew Powell's side, in the hot zone, with everything she needs to save his life if he is injured or falls ill. Her job gets even harder when Powell embarks on the campaign trail, accompanied by his high-profile daughter, Blair, and shadowed by paparazzi, zealots masquerading as patriots, and not-so-peaceful protesters. US Secret Service Agent Evyn Daniels, a member of the president's Personal Protection Detail (the elite PPD), is assigned to indoctrinate the new head of the WHMU in the necessary protocols--a job she wouldn't have to do if the right person had gotten the job, her best friend, Doctor Peter Chang. As they set off on the campaign trail, Wes and Evyn declare an uneasy professional truce, while privately their relationship is heating up fast.